0076 Delayed chemotherapy and/or dose reduction. A model to accurately predict the dose-intensity
نویسندگان
چکیده
منابع مشابه
A New Model to Describe the Single-dose Pharmacokinetics of Bevacizumab and Predict Its Multiple-Dose Pharmacokinetics in Beagle Dogs
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Complex pharmacokinetic (PK) properties including nonlinear elimination were encountered by some monoclonal antibodies (mAbs), and classic compartment models sometimes failed to appropriately describe those properties. In this work, a new model was built on a comprehensive analysis of the complex elimination of mAbs. This new model was firstly utilized to fit with the single-dose plasma concent...
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Background It is remain a main concern that pediatric chest radiographies contribute to the significant radiation exposure to the thyroid gland as a more susceptible organ to radiation induced cancer. The aim of this study was to evaluate the entrance surface dose (ESD) of pediatric chest radiography compared to the diagnostic reference levels (DRL) and evaluation the efficacy of the lead (Pb)...
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The most important variables for the clinical use of antitumor agents (AAs) are dose and combination chemotherapy. The objectives of this study were to analyze the relationship between these two variables and to propose a unified conceptual framework for the construct and interpretation of clinical trials. Definitions and variables with respect to dose include potency, therapeutic index, standa...
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ژورنال
عنوان ژورنال: The Breast
سال: 2009
ISSN: 0960-9776
DOI: 10.1016/s0960-9776(09)70121-3